T-cell origin of Lennert's lymphoma

Br J Haematol. 1986 Nov;64(3):521-8. doi: 10.1111/j.1365-2141.1986.tb02208.x.

Abstract

The arrangement of the T-cell receptor and immunoglobulin genes has been analysed in five cases of Lennert's lymphoma. All cases showed rearrangement of the gene coding for the beta chain of the T-cell receptor and a germline configuration of the immunoglobulin genes. This provides strong evidence that Lennert's lymphoma is a T-cell lymphoma.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal
  • Genotype
  • Humans
  • Immunoglobulins / genetics
  • Lymphoma / genetics*
  • Lymphoma / immunology
  • Receptors, Antigen, T-Cell / genetics
  • T-Lymphocytes / immunology*

Substances

  • Antibodies, Monoclonal
  • Immunoglobulins
  • Receptors, Antigen, T-Cell