Trichloroacetic Acid Paint for Boxcar and Polymorphic Acne Scars

Dermatol Surg. 2022 Feb 1;48(2):214-218. doi: 10.1097/DSS.0000000000003339.

Abstract

Background: Scarring is a common complication of acne vulgaris with a significant impact on the psychological well-being of patients. Focal application of high concentration trichloroacetic acid (TCA) has been proven efficacious in treating ice-pick scars, but the utility in other scar types is understudied.

Objective: The aim of this study is to evaluate the efficacy and safety of 90% TCA in boxcar and polymorphic acne scars using a novel brush applicator.

Materials and methods: Forty-one patients with acne scars were recruited for treatment of boxcar and polymorphic scar with 90% TCA applied with a cosmetic brush. Each patient received 3 treatment sessions spaced between 7 and 9 weeks apart.

Results: All participants had good to excellent outcomes as per Jacob and colleagues grading. Patients with skin Type 3 to 6 had more excellent outcomes (13 patient, 59%) than patients of skin type 1 to 2 (9 patients, 41%). Two participants (5%) had postprocedural complications. Five participants (14%) were on concomitant isotretinoin with no appreciable increase in reepithelialization time or rate of complications.

Conclusion: Focal 90% TCA with a cosmetic brush applicator is safe and effective in treating boxcar and polymorphic scars. The clinical outcome is good to excellent with low rates of complication.

MeSH terms

  • Acne Vulgaris* / surgery
  • Cicatrix / etiology
  • Cicatrix / pathology
  • Cicatrix / therapy
  • Humans
  • Paint
  • Treatment Outcome
  • Trichloroacetic Acid* / adverse effects

Substances

  • Trichloroacetic Acid