Ground-glass opacity on emergency department chest X-ray: a risk factor for in-hospital mortality and organ failure in elderly admitted for COVID-19

Postgrad Med. 2023 Apr;135(3):265-272. doi: 10.1080/00325481.2021.2021741. Epub 2022 Jan 6.

Abstract

Introduction: Ground-glass opacity is commonly seen on radiographic imaging tests of patients admitted for COVID-19. The main objective of this study is to determine if the presence of ground-glass opacity on chest X-rays carried out at the Emergency Department correlates with significantly higher mortality. A secondary objective is to clarify which characteristics are associated with those patients who presented ground-glass opacity.

Methods: Data were obtained from our 2020 hospital admission records. Consequently, this is a retrospective cohort study. Our cohort consists of 300 admissions from a group of elderly with a mean age of 81.6. There were 49.3% women (148/300) and 50.7% men (152/300).

Results: The presence of ground-glass opacity on chest X-rays is a risk factor for in-hospital mortality (RR = 1.6), heart failure (RR = 4.3), respiratory failure (RR = 1.5), acute kidney injury (RR = 1.3) and ICU admission (RR = 2.7).

Conclusion: Based on these results, the variable 'finding ground-glass opacity on chest X-rays carried out at the Emergency Department' should be assessed for inclusion in the different calculators that estimate the prognosis/mortality rate of patients admitted for COVID-19.

Keywords: COVID-19; chest X-ray; elderly; ground-glass opacity; mortality; organ failure.

MeSH terms

  • Aged
  • Aged, 80 and over
  • COVID-19*
  • Emergency Service, Hospital
  • Female
  • Hospital Mortality
  • Humans
  • Male
  • Retrospective Studies
  • Risk Factors
  • Tomography, X-Ray Computed* / methods
  • X-Rays