Recurrent myocardial infarction associated with cocaine abuse in a young man with normal coronary arteries: evidence for coronary artery spasm culminating in thrombosis

J Am Coll Cardiol. 1987 Apr;9(4):964-8. doi: 10.1016/s0735-1097(87)80256-5.


Myocardial infarction is increasingly recognized as a complication of cocaine abuse. A significant number of persons suffering from myocardial infarction associated with cocaine abuse do not have significant coronary atherosclerosis, and the mechanism for infarction in these patients has remained obscure. This report describes a young man with angiographically normal coronary arteries in whom cocaine abuse produced coronary artery spasm leading to coronary thrombosis and infarction.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cardiac Catheterization
  • Cocaine*
  • Coronary Angiography
  • Coronary Artery Bypass
  • Coronary Vasospasm / chemically induced
  • Electrocardiography
  • Humans
  • Male
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / etiology*
  • Myocardial Infarction / surgery
  • Recurrence
  • Substance-Related Disorders / complications*


  • Cocaine