Application of 3-dimensional printing implants for bone tumors

Clin Exp Pediatr. 2022 Oct;65(10):476-482. doi: 10.3345/cep.2021.01326. Epub 2021 Dec 23.


Three-dimensional (3D) additive manufacturing has recently been used in various medical fields. Among them, orthopedic oncology is one that utilizes it most actively. Bone and tumor modeling for surgical planning, personalized surgical instrument fabrication, and implant fabrication are typical applications. The 3D-printed metal implants using titanium alloy powder have created a revolutionary change in bone reconstruction that can be customized to all body areas; however, bioprinting remains experimental and under active study. This review explores the practical applications of 3D printing in orthopedic oncology and presents a representative case. The 3D-printed implant can replace the conventional tumor prosthesis and auto/allobone graft, thereby personalizing bone reconstruction. Biologic bone reconstruction using biodegradable or bioprinted materials beyond metal may be possible in the future.

Keywords: Additive manufacturing; Bone tumor; Implant; Limb salvage surgery; Three-dimensional printing.