Herbal Products Used in Menopause and for Gynecological Disorders

Molecules. 2021 Dec 8;26(24):7421. doi: 10.3390/molecules26247421.


Herbal products are often used as an alternative to pharmacological therapy. Menopausal symptoms and gynecological disorders (such as premenstrual syndrome and dysmenorrhea) are the indications where pharmacological therapy may have serious adverse events, hence many women prefer to use herbal products to help with these symptoms. Here, we reviewed plants and derived products, which are commonly used for the abovementioned indications, focusing on clinical data, safely profile and whether or not their use is justified. We noted that limited data are available on the use of some plants for alleviating the symptoms of menopause and gynecological disorders. While black cohosh (Cimicifuga racemose) and red clover (Trifolium pretense) were consistently shown to help reduce menopausal symptoms in clinical studies, currently available data do not fully support the use of fenugreek (Trigonella foenum-graecum), hops (Humulus lupulus), valerian (Valeriana officinalis), and soybean (Glycine max and Glycine soja) for this indication. For premenstrual syndrome and premenstrual dysphoric disorder, chaste tree (Vitex agnus-castus) shows effectiveness, but more clinical studies are needed to confirm such effect upon the use of evening primrose (Oenothera biennis).

Keywords: dysmenorrhea; gynecological disorders; herbal products; medicinal plants; menopause; premenstrual syndrome.

Publication types

  • Review

MeSH terms

  • Dysmenorrhea / drug therapy*
  • Female
  • Humans
  • Menopause / drug effects*
  • Phytotherapy*
  • Plants, Medicinal*
  • Premenstrual Syndrome / drug therapy*