Radiotherapy of sinonasal cancers

Cancer Radiother. 2022 Feb-Apr;26(1-2):156-167. doi: 10.1016/j.canrad.2021.10.007. Epub 2021 Dec 22.


We present the update of the recommendations of the French society of radiotherapy and oncology on the indications and the technical methods of carrying out radiotherapy of sinonasal cancers. Sinonasal cancers (nasal fossae and sinus) account for 3 to 5% of all cancers of the head and neck. They include carcinomas, mucosal melanomas, sarcomas and lymphomas. The management of sinonasal cancers is multidisciplinary but less standardized than that of squamous cell carcinomas of the upper aerodigestive tract. As such, patients with sinonasal tumors can benefit from the expertise of the French expertise network for rare ENT cancers (Refcor). Knowledge of sinonasal tumour characteristics (histology, grade, risk of lymph node involvement, molecular characterization, type of surgery) is critical to the determination of target volumes. An update of multidisciplinary indications and recommendations for radiotherapy in terms of techniques, target volumes and radiotherapy fractionation of the French society of radiotherapy and oncology (SFRO) was reported in this manuscript.

Keywords: Cancer; Dose; French Society of Oncological Radiotherapy; Radiotherapy; Radiothérapie; Recommandations; Recommendations; Rhinosinusien; Sinonasal; Sinus; Société française de radiothérapie oncologique; Target volume; Volume cible.

Publication types

  • Practice Guideline

MeSH terms

  • Adenocarcinoma / radiotherapy
  • Adenocarcinoma / surgery
  • Carcinoma, Adenoid Cystic / radiotherapy
  • Carcinoma, Adenoid Cystic / surgery
  • Carcinoma, Neuroendocrine / radiotherapy
  • Carcinoma, Neuroendocrine / surgery
  • Carcinoma, Squamous Cell / radiotherapy
  • Carcinoma, Squamous Cell / surgery
  • Esthesioneuroblastoma, Olfactory / radiotherapy
  • Esthesioneuroblastoma, Olfactory / surgery
  • France
  • Humans
  • Lymphoma / therapy
  • Melanoma / radiotherapy
  • Melanoma / therapy
  • Nasal Cavity* / diagnostic imaging
  • Nose Neoplasms / diagnostic imaging
  • Nose Neoplasms / radiotherapy*
  • Nose Neoplasms / surgery
  • Organs at Risk
  • Paranasal Sinus Neoplasms / diagnostic imaging
  • Paranasal Sinus Neoplasms / radiotherapy
  • Paranasal Sinus Neoplasms / surgery
  • Patient Positioning
  • Radiation Oncology
  • Sarcoma / radiotherapy
  • Sarcoma / surgery
  • Societies, Medical