The emerging role of real-world data in advanced breast cancer therapy: Recommendations for collaborative decision-making

Breast. 2022 Feb:61:118-122. doi: 10.1016/j.breast.2021.12.015. Epub 2021 Dec 22.


Among stakeholders and decision-makers in advanced breast cancer, the demand for insights from real-world data (RWD) is increasing. Although RWD can be used to support decisions throughout different stages of a breast cancer drug's life cycle, barriers exist to its use and acceptance. We propose a collaborative approach to generating and using RWD that is meaningful to multiple stakeholders, and encourage frameworks toward international guidelines to help standardize RWD methodologies to achieve more efficient use of RWD insights.

Keywords: Breast cancer; Cancer; Decision-making; Patient advocacy; Real-world data (RWD); Real-world evidence (RWE).

MeSH terms

  • Breast Neoplasms* / drug therapy
  • Female
  • Humans