Recent Progress in Applicability of Exercise Immunology and Inflammation Research to Sports Nutrition

Nutrients. 2021 Nov 28;13(12):4299. doi: 10.3390/nu13124299.

Abstract

This article focuses on how nutrition may help prevent and/or assist with recovery from the harmful effects of strenuous acute exercise and physical training (decreased immunity, organ injury, inflammation, oxidative stress, and fatigue), with a focus on nutritional supplements. First, the effects of ketogenic diets on metabolism and inflammation are considered. Second, the effects of various supplements on immune function are discussed, including antioxidant defense modulators (vitamin C, sulforaphane, taheebo), and inflammation reducers (colostrum and hyperimmunized milk). Third, how 3-hydroxy-3-methyl butyrate monohydrate (HMB) may offset muscle damage is reviewed. Fourth and finally, the relationship between exercise, nutrition and COVID-19 infection is briefly mentioned. While additional verification of the safety and efficacy of these supplements is still necessary, current evidence suggests that these supplements have potential applications for health promotion and disease prevention among athletes and more diverse populations.

Keywords: anti-inflammatory substances; antioxidant; exercise; functional foods; immunity; inflammation; metabolism; muscle damage; oxidative stress; training.

Publication types

  • Review

MeSH terms

  • Antioxidants / therapeutic use*
  • Athletes*
  • COVID-19 / epidemiology
  • COVID-19 / immunology
  • Dietary Supplements*
  • Exercise / immunology*
  • Humans
  • Inflammation / epidemiology
  • Inflammation / immunology
  • Oxidative Stress* / drug effects
  • Oxidative Stress* / immunology
  • Physical Endurance* / drug effects
  • Physical Endurance* / immunology
  • SARS-CoV-2 / immunology
  • Sports Nutritional Sciences

Substances

  • Antioxidants