Curcumin in Metabolic Health and Disease

Nutrients. 2021 Dec 11;13(12):4440. doi: 10.3390/nu13124440.


In recent years, epidemiological studies have suggested that metabolic disorders are nutritionally dependent. A healthy diet that is rich in polyphenols may be beneficial in the treatment of metabolic diseases such as polycystic ovary syndrome, metabolic syndrome, non-alcoholic fatty liver disease, cardiovascular disease, and, in particular, atherosclerosis. Curcumin is a polyphenol found in turmeric and has been reported to have antioxidant, anti-inflammatory, hepatoprotective, anti-atherosclerotic, and antidiabetic properties, among others. This review summarizes the influence of supplementation with curcumin on metabolic parameters in selected metabolic disorders.

Keywords: atherosclerosis; curcumin; metabolic diseases; metabolic syndrome; nanocurcumin; non-alcoholic fatty liver syndrome; polycystic ovary syndrome.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents
  • Antioxidants
  • Atherosclerosis / drug therapy
  • Atherosclerosis / prevention & control
  • Cardiovascular Diseases / drug therapy
  • Cardiovascular Diseases / prevention & control
  • Curcuma / chemistry
  • Curcumin / administration & dosage*
  • Curcumin / isolation & purification
  • Curcumin / pharmacology*
  • Dietary Supplements*
  • Female
  • Humans
  • Hypoglycemic Agents
  • Male
  • Metabolic Diseases / drug therapy*
  • Metabolic Diseases / prevention & control
  • Non-alcoholic Fatty Liver Disease / drug therapy
  • Phytotherapy*
  • Polycystic Ovary Syndrome / drug therapy


  • Anti-Inflammatory Agents
  • Antioxidants
  • Hypoglycemic Agents
  • Curcumin