Decision Support System for Breast Cancer Detection Using Biomarker Indicators

Adv Exp Med Biol. 2021;1338:13-19. doi: 10.1007/978-3-030-78775-2_3.


Breast cancer is the second most common type of cancer among women in the USA, and it is very common to appear in its invasive form. Detecting its presence in the early stages can potentially aid in the mortality rate depletion since at that point large tumours are highly unlikely to have developed. Technological advances of the last decades have provided advanced tools that employ machine learning for early detection. Common techniques include tumour imaging using special equipment that in most cases is not widely accessible. In order to overcome this limitation, new techniques that employ blood-based biomarkers are being explored. In the current work machine learning algorithms are exploited for the development of a decision support system for breast cancer using easily obtainable user information, age, body mass index, glucose and resistin. The explored algorithms include Logistic Regression, Naive Bayes, Support Vector Machine and Gradient Boosting Classification, all of which are used for the classification of new patients based on a dataset that includes information from previous breast cancer incidents. The results depict that the optimal algorithm based on the current methodology and implementation is the Gradient Boosting Classification which exhibits the highest prediction scores. In order to ensure wide accessibility, a mobile application is developed. The user can easily provide the required information for the prediction to the application and obtain the results rapidly.

Keywords: Biomarkers; Breast cancer detection; Cancer detection; Decision support systems; Machine learning.

MeSH terms

  • Bayes Theorem
  • Breast Neoplasms* / diagnosis
  • Female
  • Humans
  • Logistic Models
  • Machine Learning
  • Support Vector Machine