Research advances in Dieulafoy's disease of the bronchus (Review)

Xiqian Xing; Jie Liu; Shuanglan Xu; Yishu Deng; Jiao Yang

doi:10.3892/etm.2021.11023

Research advances in Dieulafoy's disease of the bronchus (Review)

Exp Ther Med. 2022 Jan;23(1):100. doi: 10.3892/etm.2021.11023. Epub 2021 Dec 1.

Authors

Xiqian Xing¹, Jie Liu¹, Shuanglan Xu¹, Yishu Deng¹, Jiao Yang²

Affiliations

¹ Department of Respiratory Medicine, The Affiliated Hospital of Yunnan University, The Second People's Hospital of Yunnan Province, Kunming, Yunnan 650021, P.R. China.
² First Department of Respiratory Medicine, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, P.R. China.

Abstract

Dieulafoy's disease is characterized by abnormal submucosal arteries and results in acute luminal hemorrhage. Dieulafoy's lesions can also be found in the submucosa of the bronchus. Due to its low incidence rate and non-specific clinical symptoms, Dieulafoy's disease is easy to overlook, but can lead to massive bleeding and high rates of mortality. Therefore, improvements in the understanding of the disease are necessary. The awareness of the disease and associated diagnostic and treatment techniques have continued to improve, and thus, an increasing number of cases of Dieulafoy's disease of the bronchus have been reported. In the present review, 74 cases of Dieulafoy's disease are summarized. New technologies such as endobronchial ultrasound, narrow-band imaging, angiography and argon plasma treatment have been found to be increasingly applied to diagnose and treat Dieulafoy's disease of the bronchus. Therefore, the primary focus of this systematic review is to highlight advances in the diagnosis and treatment of bronchial Dieulafoy's disease.

Keywords: Dieulafoy's disease; bronchi; diagnosis; outcome; treatment.

Publication types

Review

Grants and funding

Funding: The present study was supported by the Special and Joint Program of the Yunnan Provincial Science and Technology Department and Kunming Medical University [grant no. 2018FE001(-206)], the Yunnan Health Training Project of High Level Talents (grant no. and H-2018095), the Young Academic and Technical Leaders of Yunnan Province (grant no. 2017HB053), the Science and Technology Program for Public Wellbeing of Yunnan Province (grant no. 2014RA020).and the Famous Doctors of High-level Talent Training Support Program of Yunnan Province (grant nos. YNWR-MY-2020-013 and YNWR-MY-2020-027).