In hypertension, a quadpill containing quarter doses of 4 BP drugs reduced BP at 12 wk vs. standard-dose monotherapy

Krysta Brown; Anthony A Donato Md

doi:10.7326/J21-0003

In hypertension, a quadpill containing quarter doses of 4 BP drugs reduced BP at 12 wk vs. standard-dose monotherapy

Ann Intern Med. 2022 Jan;175(1):JC3. doi: 10.7326/J21-0003. Epub 2022 Jan 4.

Authors

Krysta Brown¹, Anthony A Donato Md¹

Affiliation

¹ Tower Health/Reading Hospital, West Reading, Pennsylvania, USA (K.B., A.A.D.).

PMID: 34978861
DOI: 10.7326/J21-0003

Abstract

Chow CK, Atkins ER, Hillis GS, et al. Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial. Lancet. 2021;398:1043-52. 34469767.

Publication types

Comment

MeSH terms

Amlodipine / pharmacology
Amlodipine / therapeutic use
Antihypertensive Agents / therapeutic use
Blood Pressure / drug effects
Double-Blind Method
Drug Therapy, Combination
Humans
Hypertension* / drug therapy
Pharmaceutical Preparations*

Substances

Antihypertensive Agents
Pharmaceutical Preparations
Amlodipine