Single cell RNA-seq analysis identifies a noncoding RNA mediating resistance to sorafenib treatment in HCC

Mol Cancer. 2022 Jan 3;21(1):6. doi: 10.1186/s12943-021-01473-w.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers, Tumor*
  • Carcinoma, Hepatocellular / diagnosis
  • Carcinoma, Hepatocellular / drug therapy
  • Carcinoma, Hepatocellular / genetics
  • Drug Resistance, Neoplasm / genetics*
  • Epithelial-Mesenchymal Transition
  • Gene Expression Profiling*
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / genetics
  • RNA, Long Noncoding*
  • Single-Cell Analysis
  • Sorafenib / pharmacology*
  • Sorafenib / therapeutic use
  • Transcriptome

Substances

  • Biomarkers, Tumor
  • RNA, Long Noncoding
  • Sorafenib