Celastrol promotes chondrocyte autophagy by regulating mTOR expression

Chin Med J (Engl). 2022 Jan 5;135(1):92-94. doi: 10.1097/CM9.0000000000001552.

Authors

Siming Dai¹, Jiankun Fan², Yue Zhang^{1

3}, Zhenyong Hao⁴, Huiming Yu¹, Zhiyi Zhang¹

Affiliations

¹ Department of Rheumatology and Immunology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China.
² The Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang 150001, China.
³ Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, Guangdong 518000, China.
⁴ Department of Orthopedic Surgery of Harbin Fifth Hospital, Harbin, Heilongjiang 150001, China.

No abstract available

MeSH terms

Apoptosis
Autophagy
Chondrocytes*
Pentacyclic Triterpenes
TOR Serine-Threonine Kinases / genetics
Triterpenes* / pharmacology

Substances

Pentacyclic Triterpenes
Triterpenes
TOR Serine-Threonine Kinases
celastrol