An unusual cause of anemia: Bean syndrome

Rev Esp Enferm Dig. 2022 Apr;114(4):243-244. doi: 10.17235/reed.2021.8522/2021.

Abstract

Bean syndrome or blue rubber bleb nevus syndrome (BRBNS) is a rare disease characterized by venous malformations (VM) of the skin, soft tissues and visceral organs, most frequently affecting the gastrointestinal (GI) tract. BRBNS is mainly sporadic but can be inherited in an autosomal pattern. The most common symptoms are GI bleeding and secondary iron deficiency anemia. Treatment is largely symptomatic.

Publication types

  • Letter

MeSH terms

  • Anemia* / complications
  • Gastrointestinal Neoplasms* / complications
  • Humans
  • Nevus, Blue* / complications
  • Skin Neoplasms* / complications

Supplementary concepts

  • Blue rubber bleb nevus syndrome