Blood pressure and heart rate monitoring in children and adolescent with Still's vibratory murmur

Blood Press Monit. 2022 Feb 1;27(1):9-13. doi: 10.1097/MBP.0000000000000557.


Background: Innocent heart murmur is common in healthy infants, children and adolescents. Although most cases are not pathologic, a murmur may be the manifestation of cardiovascular disease. It may also cause or be an indicator of blood pressure (BP) and heart rate (HR) changes.

Objective: This study aimed to document changes in BP and HR in children with Still's vibratory murmur (SVM).

Methods: This study included 226 children with SVM, and the control group included 138 healthy children that were age-, height- and weight-balanced. Patient files and our hospital registry system were retrospectively investigated for laboratory findings and electrocardiography and echocardiography results. In addition, we prospectively performed 24-h ambulatory BP monitoring in both groups.

Results: There were no statistically significant differences in 24-h, daytime and nighttime systolic BP, 24-h and nighttime diastolic BP and nighttime HR between the patient and control groups (P = ns). However, daytime diastolic BP, mean HR and daytime HR were significantly higher in patient group (P = 0.009, 0.039 and 0007, respectively).

Conclusions: We believe that in the presence of a higher HR and a higher aortic diastolic BP, which may induce hemodynamic changes in the left ventricle, flow turbulence through the aortic valve may increase, increasing the probability of hearing a murmur. ambulatory BP monitoring could be useful to obtain a better picture of these parameters during the 24-h period.

MeSH terms

  • Adolescent
  • Blood Pressure
  • Blood Pressure Monitoring, Ambulatory*
  • Child
  • Circadian Rhythm
  • Heart Murmurs
  • Heart Rate
  • Humans
  • Hypertension*
  • Retrospective Studies