Ovarian dysgenesis due to an idic(X)(q2803)

Ann Genet. 1987;30(2):98-100.


A 17-year-old female patient with gonadal dysgenesis but no other turnerian features was found to have a 46,X,idic(X)(pter----q2803:q2803----pter) karyotype in her lymphocytes. Replication of the rearranged X was consistently late and symmetrical. It is postulated that the ovarian dysgenesis usually seen in nonmosaic carriers of Xq;Xq terminal rearrangements may be secondary to a nonreactivation of the abnormal chromosome before meiosis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • DNA Replication
  • Female
  • Gonadal Dysgenesis / genetics*
  • Humans
  • Karyotyping
  • Lymphocytes / cytology
  • Sex Chromosome Aberrations*
  • X Chromosome*