Antifungal Resistance Trends of Candida auris Clinical Isolates in New York and New Jersey from 2016 to 2020

Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0224221. doi: 10.1128/aac.02242-21. Epub 2022 Jan 10.

Abstract

About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to <1% for New York C. auris clinical isolates but not for New Jersey, highlighting the regional differences.

Keywords: Candida auris; antifungals; epidemiological cutoff; minimum inhibitory concentration.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antifungal Agents* / pharmacology
  • Antifungal Agents* / therapeutic use
  • Candida auris
  • Candida*
  • Microbial Sensitivity Tests
  • New Jersey / epidemiology
  • New York / epidemiology

Substances

  • Antifungal Agents