Green Tea Consumption and Depressive Symptoms among Japanese Workers: The Furukawa Nutrition and Health Study

Nutrients. 2021 Dec 30;14(1):167. doi: 10.3390/nu14010167.


Although several cross-sectional studies have described an inverse association between green tea consumption and depressive symptoms, only one study has prospectively investigated this association. We investigated the cross-sectional and prospective associations between green tea consumption and depressive symptoms in a working population in Japan. Participants were 1987 workers who participated in the baseline survey for a cross-sectional association, and 916 participants who did not have depressive symptoms at baseline who responded to both the baseline and follow-up surveys for a prospective association. Green tea consumption was evaluated with a validated self-administered diet history questionnaire. Depression symptoms were evaluated with the Center for Epidemiologic Studies Depression (CES-D) scale. Multiple logistic regression was conducted to estimate the odds ratio of depressive symptoms based on green tea consumption. In the cross-sectional analysis, green tea consumption was not associated with the prevalence of depression symptoms. Moreover, consumption at baseline was not associated with depression symptoms after 3 years; the multivariable-adjusted odds ratio of depressive symptoms for ≥2 cups/day of green tea was 1.12 (95% confidence interval 0.65-1.91) compared with <4 cups/week after adjustment for covariates including dietary factors (trend p = 0.67). Our results suggest that there is no association of consumption of green tea with symptoms of depression in Japanese.

Keywords: Japanese; depressive symptoms; green tea; prospective study.

MeSH terms

  • Adult
  • Aged
  • Asian People
  • Cross-Sectional Studies
  • Depression / epidemiology*
  • Depression / etiology
  • Eating / physiology*
  • Female
  • Health Surveys*
  • Humans
  • Japan / epidemiology
  • Male
  • Middle Aged
  • Negative Results
  • Occupational Health*
  • Prevalence
  • Prospective Studies
  • Surveys and Questionnaires
  • Tea* / adverse effects


  • Tea