Carotid artery velocity time integral and corrected flow time measured by a wearable Doppler ultrasound detect stroke volume rise from simulated hemorrhage to transfusion

BMC Res Notes. 2022 Jan 10;15(1):7. doi: 10.1186/s13104-021-05896-y.


Objective: Doppler ultrasonography of the common carotid artery is used to infer stroke volume change and a wearable Doppler ultrasound has been designed to improve this workflow. Previously, in a human model of hemorrhage and resuscitation comprising approximately 50,000 cardiac cycles, we found a strong, linear correlation between changing stroke volume, and measures from the carotid Doppler signal, however, optimal Doppler thresholds for detecting a 10% stroke volume change were not reported. In this Research Note, we present these thresholds, their sensitivities, specificities and areas under their receiver operator curves (AUROC).

Results: Augmentation of carotid artery maximum velocity time integral and corrected flowtime by 18% and 4%, respectively, accurately captured 10% stroke volume rise. The sensitivity and specificity for these thresholds were identical at 89% and 100%. These data are similar to previous investigations in healthy volunteers monitored by the wearable ultrasound.

Keywords: Carotid Doppler; Corrected flow time; Stroke volume; Velocity time integral.

MeSH terms

  • Blood Flow Velocity
  • Carotid Arteries* / diagnostic imaging
  • Carotid Artery, Common
  • Hemorrhage
  • Humans
  • Stroke Volume
  • Ultrasonography, Doppler
  • Wearable Electronic Devices*