Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Feb 1;158(2):200-201.
doi: 10.1001/jamadermatol.2021.5485.

Interventions for Cutaneous Disease in Systemic Lupus Erythematosus: Summary of a Cochrane Review

Grant Sprow  1   2 , Mohsen Afarideh  1   2 , Victoria P Werth  1   2
Affiliations
Comment

Interventions for Cutaneous Disease in Systemic Lupus Erythematosus: Summary of a Cochrane Review

Grant Sprow et al. JAMA Dermatol. .

Abstract

Clinical question: What is the efficacy of interventions for cutaneous disease in systemic lupus erythematosus (SLE) in randomized clinical trials (RCTs)?

Bottom line: Available RCT evidence on the management of cutaneous disease in SLE is sparse and of limited quality. Among traditional options, methotrexate and hydroxychloroquine have the strongest evidence compared with placebo in the end points of complete clinical response and number of clinical flares, respectively, while chloroquine appears noninferior to methotrexate in achieving complete clinical response.

PubMed Disclaimer

Comment on

Similar articles

See all similar articles

MeSH terms