Left lower limb deep venous thrombosis, May-Thurner syndrome and endovascular management

Saudi Med J. 2022 Jan;43(1):108-112. doi: 10.15537/smj.2022.43.1.20210473.


Objectives: To determine the prevalence of May-Thurner syndrome (MTS) in left lower limb deep venous thrombosis (DVT) cases and to analyze the outcome of endovascular intervention in these patients.

Methods: A record-based descriptive study was carried out in Radiology Department, King Fahad Military Medical Complex, Dhahran, Saudi Arabia, including patients who underwent lower limb duplex ultrasounds between January 2015-2021. Patients with bilateral DVTs, known pelvic masses, and pelvic surgeries were excluded. All patients positive for DVTs were identified and further imaging was reviewed. Left common iliac vein compression of 50% or more on computed tomography (CT) was considered positive for MTS. Endovascular interventions (venoplasty alone or with stenting) were evaluated and success recorded by observing patency of vein on follow-up imaging or improvement of symptoms on follow-up visits.

Results: Of 182 patients with left lower limb duplex studies, 51 patients were positive for DVTs. A total of 37 patients had CTs and 21 patients had MTS (17 females, 3 males). A total of 15 patients underwent endovascular interventions, 2 patients had venoplasties alone (one successful) and 13 patients had venoplasties with stenting (10 successful).

Conclusion: Patients with MTS as cause of DVT may benefit from early endovascular intervention.

Keywords: May-Thurner syndrome; endovascular; iliac vein compression syndrome; venoplasty.

MeSH terms

  • Endovascular Procedures*
  • Female
  • Humans
  • Lower Extremity / diagnostic imaging
  • Lower Extremity / surgery
  • Male
  • May-Thurner Syndrome* / complications
  • May-Thurner Syndrome* / diagnostic imaging
  • May-Thurner Syndrome* / epidemiology
  • Stents
  • Treatment Outcome
  • Venous Thrombosis* / diagnostic imaging
  • Venous Thrombosis* / epidemiology
  • Venous Thrombosis* / therapy