Allocation of patients to treatment groups in a controlled clinical study

Br J Cancer. 1978 May;37(5):849-57. doi: 10.1038/bjc.1978.124.


In a controlled clinical study ("clinical trial") to compare 2 or more treatments for a disease, an objective method of allocating patients to treatment groups is needed. Various existing methods of allocation are described, including those which take account of patients' pre-treatment characteristics.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Clinical Trials as Topic
  • Humans
  • Patients
  • Prognosis
  • Random Allocation
  • Research Design*