The Launch of A Girl's First Period Study: Demystifying Reproductive Hormone Profiles in Adolescent Girls

Janet N Lucien; Madison T Ortega; Madison E Calvert; Cynthia Smith; Xiomara White; Heidi Rogers; Brittany Mosley; Ruhani Agrawal; Anna Drude; Christopher McGee; Margaret George; Audrey Brown; Kimberly Downey; Catherine Wild; Alexander Njunge; Cherie M Kuzmiak; David Zava; Theodore Zava; Jenny Pollard; Julie Francis; Breana L Beery; Margaret Harlin; Gladys Ruby Gonzalez; Natalie D Shaw

doi:10.1016/j.jpag.2021.12.018

The Launch of A Girl's First Period Study: Demystifying Reproductive Hormone Profiles in Adolescent Girls

J Pediatr Adolesc Gynecol. 2022 Aug;35(4):420-425. doi: 10.1016/j.jpag.2021.12.018. Epub 2022 Jan 11.

Authors

Janet N Lucien¹, Madison T Ortega², Madison E Calvert², Cynthia Smith², Xiomara White², Heidi Rogers², Brittany Mosley², Ruhani Agrawal², Anna Drude², Christopher McGee², Margaret George², Audrey Brown², Kimberly Downey², Catherine Wild², Alexander Njunge², Cherie M Kuzmiak³, David Zava⁴, Theodore Zava⁴, Jenny Pollard², Julie Francis², Breana L Beery², Margaret Harlin², Gladys Ruby Gonzalez², Natalie D Shaw⁵

Affiliations

¹ Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina; Division of Pediatric Endocrinology, University of North Carolina School of Medicine, Chapel Hill, North Carolina. Electronic address: janet.lucien@nih.gov.
² Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina.
³ Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
⁴ ZRT Laboratory, Beaverton, Oregon.
⁵ Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina. Electronic address: natalie.shaw@nih.gov.

Abstract

Limited data exist on the reproductive hormone dynamics that govern the transition from menarche to the establishment of the mature ovulatory cycles of a fertile young woman. It is also unclear how environmental and lifestyle factors could modulate this transition in contemporary girls. Here, we introduce A Girl's First Period Study, an ambitious longitudinal study aimed at charting the early post-menarchal course of a cohort of healthy girls in the Triangle region of North Carolina.

Keywords: Adolescent; Menarche; Menstrual cycle; Ovulation.

Publication types

Editorial

MeSH terms

Adolescent
Female
Humans
Longitudinal Studies
Luteinizing Hormone
Menarche
Menstrual Cycle*
Menstruation Disturbances
Ovulation*

Substances

Luteinizing Hormone

Abstract

Publication types

MeSH terms

Substances

Grants and funding