First Report of Cerebral Venous Thrombosis Following Inactivated-Virus Covid Vaccination (Sinopharm and Sinovac)

Sajid Hameed; Ayisha Farooq Khan; Sara Khan; Mohammad Wasay

doi:10.1016/j.jstrokecerebrovasdis.2021.106298

First Report of Cerebral Venous Thrombosis Following Inactivated-Virus Covid Vaccination (Sinopharm and Sinovac)

J Stroke Cerebrovasc Dis. 2022 Mar;31(3):106298. doi: 10.1016/j.jstrokecerebrovasdis.2021.106298. Epub 2022 Jan 13.

Authors

Sajid Hameed¹, Ayisha Farooq Khan¹, Sara Khan¹, Mohammad Wasay²

Affiliations

¹ Department of Medicine, Aga Khan University, Stadium Road, Karachi, Pakistan.
² Department of Medicine, Aga Khan University, Stadium Road, Karachi, Pakistan. Electronic address: mohammad.wasay@aku.edu.

PMID: 35033989
DOI: 10.1016/j.jstrokecerebrovasdis.2021.106298

Abstract

Cerebral venous thrombosis (CVT) is an uncommon cerebrovascular disease, which has been reported with covid infection as well as covid vaccines, particularly AstraZeneca and Janssen vaccines. We present four consecutive cases of CVT after receiving either Sinopharm or Sinovac vaccine, both of which are composed of an inactivated-virus. All the patients recovered well with anticoagulation and discharged with a good functional outcome. This is the first case series reporting CVT following the administration of these vaccines.

Keywords: CVT; Cerebral venous thrombosis; Sinopharm; Sinovac; Vaccine.

Publication types

Case Reports

MeSH terms

COVID-19 Vaccines* / administration & dosage
COVID-19 Vaccines* / adverse effects
Humans
Intracranial Thrombosis* / etiology
Vaccines, Inactivated / administration & dosage
Vaccines, Inactivated / adverse effects

Substances

COVID-19 Vaccines
Vaccines, Inactivated