Gender differences in degenerative lumbar scoliosis spine flexibilities

Jie Zheng; Boyle Cheng; Daniel Cook; Yonghong Yang

Gender differences in degenerative lumbar scoliosis spine flexibilities

Am J Transl Res. 2021 Dec 15;13(12):13959-13966. eCollection 2021.

Authors

Jie Zheng¹, Boyle Cheng², Daniel Cook², Yonghong Yang¹

Affiliations

¹ First Department of Orthopaedics, The 903 Hospital of PLA No. 14 Lingyin Road, Hangzhou 310012, Zhejiang, China.
² Department of Neurosurgery, Spine and Biomechanics Laboratory, Allegheny Health Network No. 320 East North Avenue, Pittsburgh 15212, PA, USA.

PMID: 35035737
PMCID: PMC8748112

Abstract

Objectives: The incidence of adolescent idiopathic scoliosis is higher in girls, but spine deformities are more severe in boys. We aimed to identify gender differences of mechanical factors involved in adult degenerative scoliosis (DS).

Methods: 20 male (60.35±6.77 years) and 19 female (58.89±9.15 years) specimens of cadaveric lumbar spines were divided into 3 groups comprised of a Cobb angle >10° (DS), a Cobb angle <10° but >3° (pre-degenerative scoliosis (PS)) and intervertebral disc angles <3° in which the Cobb angle could not be measured (non-degenerative scoliosis (NS)), respectively. Spine data were collected for flexion/extension (FE), lateral bending (LB), axial torsion (AT), range of motion (ROM), neutral zone (NZ) and the neutral zone ratio (NZR).

Results: There was no significant difference regarding the severity of DS between male and female specimens. Only in males were ROM_AT (P=0.001), NZ_AT (P<0.001), NZ_FE (P=0.045), NZ_LB (P=0.002) as well as NZR_AT (P<0.001) and NZR_LB (P=0.001) values significantly lower in right compared to left scoliosis. With the exception of ROM_AT in DS specimens, ROM_AT, ROM_FE and ROM_LB values were significantly higher in females than those in males for the DS, PS and NS specimens. NZ_AT, NZ_FE and NZ_LB values were significantly higher in PS and NS female specimens. NZR_AT was significantly lower in female DS specimens (P=0.031) and significantly higher in female PS specimens (P=0.031) compared to that in male specimens.

Conclusions: In lumbar scoliosis specimens, the rigidness of spines was higher in males than in females and more pronounced in right than in left scoliosis, but only in males.

Keywords: Biomechanics; degenerative scoliosis; development; initial scoliosis nature; occurrence.