A fatal case of COVID-19 breakthrough infection due to the delta variant

Elio Bignardi; Claudia Brogna; Chiara Capasso; Barbara Brogna

doi:10.1002/ccr3.5232

A fatal case of COVID-19 breakthrough infection due to the delta variant

Clin Case Rep. 2022 Jan 11;10(1):e05232. doi: 10.1002/ccr3.5232. eCollection 2022 Jan.

Authors

Elio Bignardi¹, Claudia Brogna^{2

3}, Chiara Capasso⁴, Barbara Brogna⁵

Affiliations

¹ Radiology Unit "Cotugno Hospital" Naples Italy.
² Pediatric Neurology Unit Fondazione Policlinico Universitario "A. Gemelli", IRCSS Rome Italy.
³ Neuropsychiatric Unit ASL Avellino Avellino Italy.
⁴ Pharmacology Department "Frangipane" Hospital ASL Avellino Ariano Irpino Italy.
⁵ Department of Radiology San Giuseppe Moscati Hospital Avellino Italy.

Abstract

COVID-19 infections that occur at least 2 weeks after complete vaccination are known as breakthrough infections. Herein, we report a clinical case resembling breakthrough infection that was correlated with a higher score of COVID-19 pneumonia on chest computed tomography (CT) in a patient who resulted positive for the delta variant and who died during the hospitalization.

Keywords: COVID‐19; COVID‐19 breakthrough infections; SARS‐CoV‐2 variants; immunodepressive state; therapy.

Publication types

Case Reports