Minimal Information about MHC Multimers (MIAMM)

J Immunol. 2022 Feb 1;208(3):531-537. doi: 10.4049/jimmunol.2100961.


With the goal of improving the reproducibility and annotatability of MHC multimer reagent data, we present the establishment of a new data standard: Minimal Information about MHC Multimers ( Multimers are engineered reagents composed of a ligand and a MHC, which can be represented in a standardized format using ontology terminology. We provide an online Web site to host the details of the standard, as well as a validation tool to assist with the adoption of the standard. We hope that this publication will bring increased awareness of Minimal Information about MHC Multimers and drive acceptance, ultimately improving the quality and documentation of multimer data in the scientific literature.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • HLA-A Antigens / immunology*
  • Humans
  • Indicators and Reagents / chemistry*
  • Internet
  • Major Histocompatibility Complex / genetics*
  • Multiprotein Complexes / chemistry
  • T-Lymphocytes / immunology*


  • HLA-A Antigens
  • Indicators and Reagents
  • Multiprotein Complexes