Childhood T-cell malignancy resembling adult T-cell leukemia/lymphoma

D R Head; C R Kjeldsberg; M E Kadin; T Pick; B Bybee; J Longbotham; E Shumski

Childhood T-cell malignancy resembling adult T-cell leukemia/lymphoma

Hematol Pathol. 1987;1(1):15-25.

Authors

D R Head¹, C R Kjeldsberg, M E Kadin, T Pick, B Bybee, J Longbotham, E Shumski

Affiliation

¹ Department of Pathology, University of Utah Medical Center, Salt Lake City 84132.

PMID: 3504428

Abstract

We describe two childhood cases of a T-cell malignancy indistinguishable from nonendemic, idiopathic adult T-cell leukemia/lymphoma. The cases illustrate the heterogeneity of nonendemic, idiopathic ATLL, including the presence of mediastinal masses and more heterogeneous immunologic markers than endemic cases, and represent the two youngest cases of ATLL yet described. The differential diagnosis of nonendemic, idiopathic ATLL is discussed.

Publication types

Case Reports

MeSH terms

Acid Phosphatase / analysis
Adolescent
Biomarkers / analysis
Bone Marrow / pathology
Child
Diagnosis, Differential
Female
Humans
Karyotyping
Leukemia-Lymphoma, Adult T-Cell / pathology*
Lymph Nodes / pathology
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology*
Skin / pathology

Substances

Biomarkers
Acid Phosphatase