[A Case Report of an Appendiceal Goblet Cell Carcinoid]

Gan To Kagaku Ryoho. 2021 Dec;48(13):1579-1581.
[Article in Japanese]


A 56-year-old woman complaining of right lower abdominal pain was admitted to our hospital. An abdominal computed tomography showed the enlarged appendix tip and a high density area around the appendix to retroperitoneum. The patient was diagnosis with acute appendicitis and underwent emergency laparoscopic appendectomy. Histopathological findings of the resected specimens revealed a component with signet ring cell carcinoma morphology that was positive for neuroendocrine markers by immunohistochemical staining, which led to the diagnosis of goblet cell carcinoid(GCC)of appendix. GCC cells were found to infiltrate the surrounding serosa and Ly positive. An additional laparoscopic ileocecal resection with D3 dissection was performed. In the appendix GCC, additional resection is considered because the lymph node metastasis rate increases(SS/13%)as the depth of wall progresses. Appendiceal tumors including GCC may develop acute appendicitis and may be followed by additional resection. Therefore, it is important to consider how to deal with the first surgery.

Publication types

  • Case Reports

MeSH terms

  • Appendectomy
  • Appendiceal Neoplasms* / surgery
  • Appendicitis* / surgery
  • Appendix* / surgery
  • Carcinoid Tumor* / surgery
  • Female
  • Humans
  • Middle Aged