A retrospective study on the etiological exploration of osteoporosis in aging men in a French geriatric setting

Ann Endocrinol (Paris). 2022 Apr;83(2):109-113. doi: 10.1016/j.ando.2022.01.002. Epub 2022 Jan 20.

Abstract

Introduction: Osteoporosis in older men is common and causes significant mortality and morbidity. Some data suggest that conditions leading to bone fragility, including osteoporosis, are under-identified and undertreated in men. Additionally, 50% of the causes of osteoporosis are secondary in men. The latest Endocrine Society and different Rheumatology Societies Guidelines recommend additional laboratory investigations in men with osteoporosis so as to treat them more efficiently.

Main goal of the study: Our aim was to determine whether men managed in our geriatrics center, diagnosed with osteoporosis, underwent investigations to determine the aetiology of osteoporosis and other bone fragility conditions and what the secondary causes were.

Materials and method: We conducted a monocentric, retrospective study including all men seen at the geriatric consult in 2016 diagnosed with osteoporosis. For each patient, we evaluated our clinical practice, whether common secondary causes were sought-after and what these aetiologies were.

Results: Among the 121 men with a diagnosis of osteoporosis seen at the geriatric consult at the Lille University Hospital in 2016, only 51 had undergone further investigations. Among the 3 major secondary causes were identified: 17.6% glucocorticoid induced, 13.7% treatment induced hypogonadism, 11.7% late onset hypogonadism.

Conclusions: A more efficient etiological assessment of osteoporosis in older men could be achieved and would improve management for our patients. This can be achieved by a better knowledge of the recommendations for etiological assessment of bone fragility and osteoporosis and a dedicated consultation within the geriatric sector.

Keywords: Aging; Déficit androgénique lié à l’âge; Geriatrics; Late onset hypogonadism; Osteoporosis; Ostéoporose; Vieillissement.

MeSH terms

  • Aged
  • Aging
  • Bone Density
  • Female
  • Humans
  • Hypogonadism* / complications
  • Male
  • Osteoporosis* / epidemiology
  • Osteoporosis* / etiology
  • Retrospective Studies