Use of oral contraceptives and risk of pancreatic cancer in women: A recalculated meta-analysis of prospective cohort studies

World J Gastroenterol. 2021 Dec 28;27(48):8374-8377. doi: 10.3748/wjg.v27.i48.8374.

Abstract

In a recent systematic review and meta-analysis of observational studies, the author found potential errors in the selection and extraction processes. The recalculated summary relative risks and the results of a dose-response meta-analysis showed that oral contraceptive use may not be associated with the risk of pancreatic cancer in women.

Keywords: Meta-analysis; Oral contraceptives; Pancreas neoplasms; Risk assessment; Risk factor; Systematic review.

Publication types

  • Meta-Analysis

MeSH terms

  • Contraceptives, Oral* / adverse effects
  • Female
  • Humans
  • Pancreatic Neoplasms* / chemically induced
  • Pancreatic Neoplasms* / epidemiology
  • Prospective Studies
  • Risk
  • Risk Factors

Substances

  • Contraceptives, Oral