Molecular Integration in Adenosine Heteroreceptor Complexes Through Allosteric and De-Phosphorylation (STEP) Mechanisms and its Role in Brain Disease

Dasiel O Borroto-Escuela; Luca Ferraro; Kjell Fuxe

doi:10.3389/fphar.2021.781381

Molecular Integration in Adenosine Heteroreceptor Complexes Through Allosteric and De-Phosphorylation (STEP) Mechanisms and its Role in Brain Disease

Front Pharmacol. 2022 Jan 5:12:781381. doi: 10.3389/fphar.2021.781381. eCollection 2021.

Authors

Dasiel O Borroto-Escuela¹, Luca Ferraro², Kjell Fuxe¹

Affiliations

¹ Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
² Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.

No abstract available

Keywords: G protein coupled receptors (GPCR); adenosine heteroreceptor complexes; adenosine receptors; allosteric modulation; dopmaine heteroreceptor complexes, mu-opioid heteroreceptor complexes; receptor-receptor interactions; striatal-enriched protein tyrosine phosphatase.