Letter to the Editor: Comments on the paper of Wylie and Korchevskiy - Carcinogenicity of fibrous glaucophane: How should we fill the data gaps?

Alessandro F Gualtieri; Dario Di Giuseppe

doi:10.1016/j.crtox.2021.100063

Letter to the Editor: Comments on the paper of Wylie and Korchevskiy - Carcinogenicity of fibrous glaucophane: How should we fill the data gaps?

Curr Res Toxicol. 2022 Jan 6:3:100063. doi: 10.1016/j.crtox.2021.100063. eCollection 2022.

Authors

Alessandro F Gualtieri¹, Dario Di Giuseppe¹

Affiliation

¹ Department of Chemical and Geological Sciences, The University of Modena and Reggio Emilia, Modena, Italy.

Abstract

Assessing the human health risk of mineral fibres is an intricate task. In the recent article by Wylie and Korchevskiy (2021) - Carcinogenicity of fibrous glaucophane: how to fill data gaps? (Curr. Res. Toxicol. Vol. 2, pp. 202-203), the authors discuss the potential toxicity and pathogenicity of fibrous glaucophane from the Franciscan Complex, California (USA). Because most of the points of discussion concerns the mineral fibre toxicity/pathogenicity model developed by our research group and the application to the case of fibrous glaucophane (Gualtieri, 2021, Curr. Res. Toxicol. Vol. 2, pp. 42-52), the aim of this Letter is to clear some basic issues, to fill some information gaps and, with a constructive spirit, to provide a complete picture on this topic.

Keywords: FPTI; Fibrous glaucophane; Mineral fibres; Pathogenicity; Toxicity.