Transience of interference in an immunoassay measuring serum levels of beta-D-glucan

Abstract

Some sera tested for 1-3-beta-D-glucan to identify invasive fungal infections exhibit interference. To assess interference transience, we evaluated results for 426 patients with an interference sample followed by a later sample. Interference was transient for 73% of patients (later sample negative or positive); median time between samples was 8 days.

Keywords: Beta-D-glucan; Fungal infections; Interference.