Hepatic epithelioid hemangioendothelioma: A clinocopathological correlation

Indian J Pathol Microbiol. 2022 Jan-Mar;65(1):133-136. doi: 10.4103/ijpm.ijpm_350_21.


Primary hepatic epithelioid hemangioendothelioma (HEHE) is a rare tumor with an incidence of <0.1 per 100,000. The clinical course is variable with variable outcomes. Due to its rarity, treatment protocols, prognostic and predictive factors are not well established underscoring the need for such a study. Pathologists' awareness of this entity, a meticulous morphologic examination coupled with immunohistochemistry can aid in accurate diagnosis.

Keywords: Epithelioid; hemangioendothelioma; hepatic.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Female
  • Hemangioendothelioma, Epithelioid / diagnostic imaging
  • Hemangioendothelioma, Epithelioid / pathology*
  • Humans
  • Immunohistochemistry
  • Liver Neoplasms / classification
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / pathology*
  • Male
  • Middle Aged
  • Prognosis
  • Tomography, X-Ray Computed
  • Young Adult