Parosmia and dysgeusia after intravenous propofol-based general anesthesia: A case report

Ann Card Anaesth. 2022 Jan-Mar;25(1):112-115. doi: 10.4103/aca.ACA_93_21.


Various drugs, including anesthetic agents, can cause parosmia in the perioperative period. There are reported cases of patients with alterations of smell and taste due to local anesthetics, nerve damage, or as a side effect of general anesthesia. We present a case of a 58-year-old male who developed parosmia and dysgeusia in the postoperative period after radical nephrectomy and inferior vena cava thrombectomy. The anesthetics used were fentanyl and propofol for general anesthesia and ropivacaine for epidural analgesia. Clinical examination did not reveal any pathology.

Keywords: Dysgeusia; effects of propofol; parosmia; postoperative olfactory disorder.

Publication types

  • Case Reports

MeSH terms

  • Anesthesia, General / adverse effects
  • Anesthesia, Intravenous
  • Anesthetics, Intravenous / adverse effects
  • Anesthetics, Local / therapeutic use
  • Dysgeusia / drug therapy
  • Fentanyl / adverse effects
  • Humans
  • Male
  • Middle Aged
  • Olfaction Disorders* / drug therapy
  • Pain, Postoperative / drug therapy
  • Propofol* / adverse effects


  • Anesthetics, Intravenous
  • Anesthetics, Local
  • Fentanyl
  • Propofol