Clinical Applications of Aspirin as a Multi-potent Drug Beyond Cardiovascular Implications: A Proof of Concept for Anesthesiologists- A Narrative Review

Aysa Rezabakhsh; Ata Mahmoodpoor; Maryam Soleimanpour; Kavous Shahsavarinia; Hassan Soleimanpour

doi:10.5812/aapm.118909

Clinical Applications of Aspirin as a Multi-potent Drug Beyond Cardiovascular Implications: A Proof of Concept for Anesthesiologists- A Narrative Review

Anesth Pain Med. 2021 Oct 31;11(5):e118909. doi: 10.5812/aapm.118909. eCollection 2021 Oct.

Authors

Aysa Rezabakhsh¹, Ata Mahmoodpoor², Maryam Soleimanpour³, Kavous Shahsavarinia⁴, Hassan Soleimanpour⁵

Affiliations

¹ Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
² Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
³ Social Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
⁴ Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
⁵ Emergency Medicine Research Team, Tabriz University of Medical Sciences, Tabriz, Iran.

Abstract

To the best of our knowledge, aspirin (ASA) is known as a commonly used medication worldwide. Although the cardiovascular aspects of ASA are well-established, recently, it has been identified that ASA can yield multiple extra-cardiovascular therapeutic potencies in facing neurodegenerative disorders, various cancers, inflammatory responses, and the COVID-19 pandemic. In this review, we aimed to highlight the proven role of ASA administration in the variety of non-cardiovascular diseases, particularly in the field of anesthesiology.

Keywords: Aspirin; Clinical Applications; Extra-Cardiovascular Diseases; Off-Label Uses.

Publication types

Review