A phototoxic drug reaction due to topical NSAIDs

Clin Case Rep. 2022 Jan 20;10(1):e05251. doi: 10.1002/ccr3.5251. eCollection 2022 Jan.


We present a case with a phototoxic reaction following topical use of NSAID. The phototoxic reaction was initially mistaken for cellulitis which led to treatment with dicloxacillin, which led to an exanthematous drug eruption. The patient was treated with topical clobetasol propionate and oral non-sedating antihistamines. Follow-up revealed post-inflammatory hypopigmentation.

Keywords: dicloxacillin; drug‐induced photosensitivity; ketoprofen; photoreaction; photosensitivity; phototoxic reaction.

Publication types

  • Case Reports