ASPICov: An automated pipeline for identification of SARS-Cov2 nucleotidic variants

PLoS One. 2022 Jan 26;17(1):e0262953. doi: 10.1371/journal.pone.0262953. eCollection 2022.

Abstract

ASPICov was developed to provide a rapid, reliable and complete analysis of NGS SARS-Cov2 samples to the biologist. This broad application tool allows to process samples from either capture or amplicon strategy and Illumina or Ion Torrent technology. To ensure FAIR data analysis, this Nextflow pipeline follows nf-core guidelines and use Singularity containers. Pipeline is implemented and available at https://gitlab.com/vtilloy/aspicov.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19 / genetics*
  • Computational Biology*
  • High-Throughput Nucleotide Sequencing*
  • Humans
  • RNA, Viral / genetics*
  • SARS-CoV-2 / genetics*
  • Whole Genome Sequencing*

Substances

  • RNA, Viral

Supplementary concepts

  • SARS-CoV-2 variants

Grants and funding

This work was supported by Santé Publique France and Région Nouvelle-Aquitaine.