Awake Surgery for Local Recurrence of Brain Metastasis in the Precentral Gyrus After Fractionated Stereotactic Radiotherapy: A Technical Case Report

Anticancer Res. 2022 Feb;42(2):1151-1155. doi: 10.21873/anticanres.15579.

Abstract

Background: To avoid permanent neurologic deficits and preserve brain function, intraoperative electrical stimulation mapping (IESM) is essential for surgical resection.

Case report: A 59-year-old right-handed woman with ovarian cancer who had undergone stereotactic radiotherapy for brain metastasis two years before, was introduced due to progressive left upper paresis. Magnetic resonance imaging showed a recurrence of the lesion. We performed awake surgery using IESM. Thus, the sensorimotor site was elicited on the precentral and postcentral gyrus. However, IESM elicited no disturbance of motor function on the surface of the posterior part of the precentral gyrus. We made a safe corticotomy on it, and performed the resection of recurrent BM. Preserving the motor and sensory function, we achieved the resection of BM. After surgery, she experienced a significant improvement in motor function.

Conclusion: IESM is a useful tool to make a safe approach via the precentral gyrus avoiding permanent sensorimotor deficits.

Keywords: Motor function; awake surgery; brain metastasis; intraoperative electrical stimulation mapping; precentral gyrus; subcortical metastasis.

Publication types

  • Case Reports
  • Technical Report

MeSH terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / radiotherapy
  • Adenocarcinoma / surgery
  • Brain Mapping / methods
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / secondary
  • Brain Neoplasms / surgery*
  • Combined Modality Therapy
  • Dose Fractionation, Radiation
  • Electric Stimulation
  • Female
  • Humans
  • Intraoperative Care / methods
  • Japan
  • Middle Aged
  • Motor Cortex / pathology
  • Motor Cortex / surgery
  • Neurosurgical Procedures / methods*
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / radiotherapy
  • Ovarian Neoplasms / surgery
  • Radiosurgery / methods
  • Wakefulness*