Spindle Cell Carcinoma of the Breast: Investigation of Magnetic Resonance Imaging Features of 26 Cases

J Comput Assist Tomogr. 2022 Jan-Feb;46(1):11-16. doi: 10.1097/RCT.0000000000001246.

Abstract

Objective: The aim of the study was to retrospectively investigate the fat-saturated T2-weighted sequences (FST2WI) and 3-dimensional dynamic contrast-enhanced sequence (DCE) of magnetic resonance imaging (MRI) findings of breast spindle cell carcinoma (SpCC).

Methods: Twenty-six women with surgically confirmed breast SpCC, who underwent breast MRI in 2 institutions, were enrolled in this study (mean age, 54 years; range, 27-81 years). Two breast radiologists determined the MRI findings by consensus after independent interpretations. Each MRI finding was analyzed.

Results: Most lesions of SpCC showed a solitary mass (92.2%). Most masses were round/oval (76.0%), had an irregular margin (88.0%), rim enhancement (72.0%), washout kinetic analysis (96.0%), hyperintensity on FST2WI (84%), hyperintensity on FST2WI and fast enhancing component on DCE (56%), and hypointense rim on FST2WI (72.0%).

Conclusions: Most breast SpCC showed a solitary mass, round/oval shape, irregular margin, rim enhancement, washout kinetics, and intratumoral hyperintensity on FST2WI; a hypointense rim on FST2WI; and hyperintensity on FST2WI and fast enhancing component on DCE.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Breast / diagnostic imaging
  • Breast / pathology
  • Breast Neoplasms* / diagnostic imaging
  • Breast Neoplasms* / pathology
  • Carcinoma* / diagnostic imaging
  • Carcinoma* / pathology
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Retrospective Studies