Biomimetic 3D living materials powered by microorganisms

Daniel Wangpraseurt; Shangting You; Yazhi Sun; Shaochen Chen

doi:10.1016/j.tibtech.2022.01.003

Biomimetic 3D living materials powered by microorganisms

Trends Biotechnol. 2022 Jul;40(7):843-857. doi: 10.1016/j.tibtech.2022.01.003. Epub 2022 Feb 1.

Authors

Daniel Wangpraseurt¹, Shangting You², Yazhi Sun², Shaochen Chen³

Affiliations

¹ Department of NanoEngineering, University of California San Diego, San Diego, CA, USA; Scripps Institution of Oceanography, University of California San Diego, San Diego, CA, USA. Electronic address: dwangpraseurt@eng.ucsd.edu.
² Department of NanoEngineering, University of California San Diego, San Diego, CA, USA.
³ Department of NanoEngineering, University of California San Diego, San Diego, CA, USA. Electronic address: chen168@eng.ucsd.edu.

PMID: 35115172
DOI: 10.1016/j.tibtech.2022.01.003

Abstract

3D bioprinting is currently widely used to build engineered mammalian tissue constructs with complex spatial structures. It has revolutionized tissue engineering and is a promising avenue for regenerative medicine. Recently, 3D bioprinting has also been used for the fabrication of living tissues that cultivate microorganisms including photosynthetic single-celled microalgae and bacterial cells. Here we review the principles and applications of biomimetic 3D living materials powered by microorganisms. We envision that there will be great potential for the application of microorganism-driven materials in biomedicine, biotechnology, and living device fabrication as well as for ecosystem restoration.

Keywords: 3D bioprinting; algae; bioenergy; hydrogel; living tissues; microbial life; symbiosis.

Publication types

Review
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Biomimetic Materials* / chemistry
Biomimetics
Bioprinting*
Ecosystem
Mammals
Printing, Three-Dimensional
Tissue Engineering
Tissue Scaffolds / chemistry