Exploiting enzymes as a powerful tool to modulate the gut microbiota

Xiaoyun Su; Bin Yao

doi:10.1016/j.tim.2022.01.003

Exploiting enzymes as a powerful tool to modulate the gut microbiota

Trends Microbiol. 2022 Apr;30(4):314-317. doi: 10.1016/j.tim.2022.01.003. Epub 2022 Feb 1.

Authors

Xiaoyun Su¹, Bin Yao²

Affiliations

¹ State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, No. 2 West Yuanmingyuan Road, Haidian District, Beijing 100193, China. Electronic address: suxiaoyun@caas.cn.
² State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, No. 2 West Yuanmingyuan Road, Haidian District, Beijing 100193, China. Electronic address: binyao@caas.cn.

PMID: 35120774
DOI: 10.1016/j.tim.2022.01.003

Abstract

Orally administered enzymes can have profound effects on the composition of the gut microbiota and may serve as an appealing alternative modulating agent. We summarize the three ways through which enzymes can influence the gut microbiota and discuss the challenges in choosing the right enzyme to modulate the gut microbiota.

Keywords: chronic disease; diabetes; enzyme; gut microbiota modulation; precision modulation; quorum sensing.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Gastrointestinal Microbiome*