Salmonella respiration turns the tables on propionate

Trends Microbiol. 2022 Mar;30(3):206-208. doi: 10.1016/j.tim.2022.01.011. Epub 2022 Feb 2.


Intestinal pathogens must combat host and microbiota-associated resistance to establish an infection. A new study (Shelton et al.) highlights how Salmonella manipulates the mammalian host to produce anaerobic respiratory electron acceptors, allowing catabolism of propionate and providing a competitive edge to Salmonella residing in the gut.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Disease Models, Animal
  • Mammals
  • Microbiota*
  • Propionates* / metabolism
  • Respiration
  • Salmonella typhimurium / metabolism


  • Propionates