Neurologic manifestations of giant cell arteritis

J Neurol. 2022 Jul;269(7):3430-3442. doi: 10.1007/s00415-022-10991-6. Epub 2022 Feb 6.


Giant cell arteritis, the most frequent form of vasculitis in persons over 50 years of age, is a granulomatous chronic vasculitis involving large and medium-sized vessels, most commonly the temporal and other cranial arteries. This common, treatable condition is associated with various clinical symptoms, including neurological ones, affecting both the central and peripheral nervous systems. In this review, we discuss the cranial and extra cranial neurological complications of giant cell arteritis, to help avoid the many pitfalls in the diagnosis of giant cell arteritis.

Keywords: GCA; Giant cell arteritis; Nerve roots; Neurological; Neuromuscular; Peripheral nerve; Stroke.

Publication types

  • Review

MeSH terms

  • Giant Cell Arteritis* / complications
  • Giant Cell Arteritis* / diagnosis
  • Humans
  • Middle Aged