Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection

Lydia L Shook; Caroline G Atyeo; Lael M Yonker; Alessio Fasano; Kathryn J Gray; Galit Alter; Andrea G Edlow

doi:10.1001/jama.2022.1206

Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection

JAMA. 2022 Mar 15;327(11):1087-1089. doi: 10.1001/jama.2022.1206.

Authors

Lydia L Shook¹, Caroline G Atyeo², Lael M Yonker³, Alessio Fasano³, Kathryn J Gray⁴, Galit Alter², Andrea G Edlow¹

Affiliations

¹ Department of Obstetrics & Gynecology, Massachusetts General Hospital, Boston.
² Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts.
³ Department of Pediatrics, Massachusetts General Hospital, Boston.
⁴ Department of Obstetrics & Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.

Abstract

This study compares the persistence of anti-spike IgG titers in infants of vaccinated mothers vs mothers who had been naturally infected with COVID-19.

Publication types

Letter
Multicenter Study
Research Support, N.I.H., Extramural

MeSH terms

Antibodies, Viral / blood*
COVID-19 / blood*
COVID-19 / immunology*
COVID-19 Vaccines*
Female
Humans
Infant
Pregnancy
Spike Glycoprotein, Coronavirus / immunology*
Time Factors

Substances

Antibodies, Viral
COVID-19 Vaccines
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2

Abstract

Publication types

MeSH terms

Substances

Grants and funding