LHRH neurons in the female C57BL/6J mouse brain during reproductive aging: no loss up to middle age

Neurobiol Aging. 1986 Jan-Feb;7(1):45-8. doi: 10.1016/0197-4580(86)90026-6.

Abstract

The numbers of neurons containing luteinizing hormone releasing hormone (LHRH) were examined with specific immunocytochemical techniques in C57BL/6J mice at 5-6 months and 15-16 months of age, the latter being the time of transition to the loss of estrous cycles. No changes were found in the organization, morphology, or numbers of LHRH neurons.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Brain / cytology
  • Brain / metabolism*
  • Gonadotropin-Releasing Hormone / metabolism*
  • Histocytochemistry
  • Hypothalamus / cytology
  • Hypothalamus / metabolism
  • Immunochemistry
  • Mice
  • Mice, Inbred C57BL

Substances

  • Gonadotropin-Releasing Hormone