Brain simulation as a cloud service: The Virtual Brain on EBRAINS

Neuroimage. 2022 May 1:251:118973. doi: 10.1016/j.neuroimage.2022.118973. Epub 2022 Feb 4.

Abstract

The Virtual Brain (TVB) is now available as open-source services on the cloud research platform EBRAINS (ebrains.eu). It offers software for constructing, simulating and analysing brain network models including the TVB simulator; magnetic resonance imaging (MRI) processing pipelines to extract structural and functional brain networks; combined simulation of large-scale brain networks with small-scale spiking networks; automatic conversion of user-specified model equations into fast simulation code; simulation-ready brain models of patients and healthy volunteers; Bayesian parameter optimization in epilepsy patient models; data and software for mouse brain simulation; and extensive educational material. TVB cloud services facilitate reproducible online collaboration and discovery of data assets, models, and software embedded in scalable and secure workflows, a precondition for research on large cohort data sets, better generalizability, and clinical translation.

Keywords: Brain modelling; Cloud; Connectome; Data protection; High performance computing; Network model; Neuroimaging; Reproducibility.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bayes Theorem
  • Brain* / diagnostic imaging
  • Cloud Computing*
  • Computer Simulation
  • Humans
  • Magnetic Resonance Imaging / methods
  • Mice
  • Software